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Anabolic Androgenic Steroid Use as a Cause of Fulminant Heart Failure
Authors:Matthew White  Erin Brennan  Kevin Yi Mi Ren  Mei Shi  Amar Thakrar
Affiliation:1. Department of Emergency Medicine, Queen’s University, Kingston, Ontario, Canada;2. Department of Critical Care, Queen’s University, Kingston, Ontario, Canada;3. Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada;4. Department of Pharmacy Services, Kingston Health Sciences Center, Kingston, Ontario, Canada;5. Division of Cardiology, Department of Medicine, Queen’s University, Kingston, Ontario, Canada
Abstract:A 39-year-old male weightlifter presented in fulminant heart failure. An echocardiogram revealed severe global biventricular failure. Left ventricular (LV) systolic function was estimated at 15%. His dilated cardiomyopathy was attributed to his use of both testosterone and boldenone in the 3-month period before his presentation. Although the deleterious effects of androgenic- anabolic steroids on diastolic function are well known, the effects of these drugs on systolic function is an area of ongoing investigation. Our case suggests that androgenic anabolic steroid use should be considered in the differential diagnosis of patients presenting with acute heart failure.
Keywords:Corresponding author: Dr Amar Thakrar   Division of Cardiology   Department of Medicine   76 Stuart Street   Kingston   Ontario   K7L 2V7   Canada. Tel.: +1-613-544-3400 x2250. fax: +1-613-544-7250.
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