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Liver abscess caused by periodontal bacterial infection with Fusobacterium necrophorum
Authors:Masato Yoneda  Shingo Kato  Hironori Mawatari  Hiroyuki Kirikoshi  Kento Imajo  Koji Fujita  Hiroki Endo  Hirokazu Takahashi  Masahiko Inamori  Noritoshi Kobayashi  Kensuke Kubota  Satoru Saito  Iwai Tohnai  Kei Watanuki  Koichiro Wada  Shin Maeda  Atsushi Nakajima
Institution:1. Division of Gastroenterology;2. Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine, Yokohama;3. Department of Pharmacology, Osaka University, Graduate School of Dentistry, Suita, Osaka, Japan
Abstract:Liver abscess is recognized as a life‐threatening disease. However, even in recent years, approximately 50% of liver abscess cases are considered to be cryptogenic. Here, we report a case of liver abscess associated with periodontal bacterial infection by Fusobacterium necrophorum, which is commonly found in the oropharyngeal flora. A 36‐year‐old man presented with fever and contrast‐enhanced abdominal computed tomography revealed multiple liver abscesses. F.necrophorum was isolated from oral smears, liver aspirates and blood samples. Liver abscesses caused by periodontal bacterial infection are rare, however, the incidence is expected to increase in the future, as periodontitis is extremely common and is on the rise as one of the most common chronic infections in the world. A systemic survey including periodontitis may be required for the exact diagnosis of the source of infection.
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