Detection of severe acute pancreatitis by contrast-enhanced magnetic resonance imaging |
| |
Authors: | A Piironen R Kivisaari E Kemppainen P Laippala A -M Koivisto V -P Poutanen L Kivisaari |
| |
Institution: | (1) Department of Radiology, Helsinki University Central Hospital, Haartmaninkatu 4, SF-00290 Helsinki, Finland, FI;(2) Department of Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, SF-00290 Helsinki, Finland, FI;(3) Department of Radiology, Tampere City Hospital, SF-33100 Tampere, Finland, FI;(4) School of Public Health, Biometry Unit, Tampere University, SF-33100 Tampere, Finland, FI |
| |
Abstract: | The aim of the study was to assess the ability of MRI to differentiate between the two forms of severity of acute pancreatitis
(AP), which is important for the detection of patients who require intensive monitoring and therapy. The second objective
was to evaluate whether the distinction would be possible regardless of the MRI equipment. Magnetic resonance imaging was
performed before and after intravenous administration of a gadolinium (Gd) chelate at 1.0 T using the breath-hold multislice
rapid gradient-echo turbo fast low-angle shot (FLASH) sequence in 14 patients, and at 1.5 T with the 2D FLASH(50) sequence
with fat saturation in 18 patients with acute pancreatitis early in the course of the disease. The patients were classified
according to the Atlanta classification system as having the mild (MAP) or severe (SAP) form of the disease. At 1.0 T with
use of a body coil, contrast-enhanced MRI failed to distinguish mild from severe pancreatitis. At 1.5 T with a phased-array
body coil, the signal intensities of the patients with SAP were statistically significantly lower than those of the MAP group.
Our initial clinical experience suggests that MRI with a sufficient magnetic field gradient strength may be useful for separating
the two forms of acute pancreatitis in their early phases.
Received: 19 January 1999; Revised: 28 May 1999; Accepted: 22 July 1999 |
| |
Keywords: | : Acute pancreatitis – Dynamic magnetic resonance imaging – Gadolinium – Pancreas – MR studies |
本文献已被 PubMed SpringerLink 等数据库收录! |
|