| 连翘化学成分研究 |
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| 引用本文： | 刘悦,宋少江,徐绥绪,符晓晖.连翘化学成分研究[J].沈阳药科大学学报,2003,20(2):101-103. |
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| 作者姓名： | 刘悦 宋少江 徐绥绪 符晓晖 |
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| 作者单位： | 沈阳药科大学中药学院,辽宁沈阳,110016 |
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| 摘 要： | 目的对中药连翘的化学成分进行分离和鉴定。方法连翘的水提物经D1 0 1大孔树脂 ,以水和不同浓度的乙醇洗脱 ,φ =60 %的乙醇洗脱部分采用硅胶吸附柱色谱的手段分离得到 4个化合物 ,利用理化和谱学分析 (IR、NMR、ESI MS)的方法进行结构鉴定。结果 4个化合物分别被鉴定为异落叶松树脂醇 (isolariciresinol) (Ⅰ ) ,丁二酸 (succinicacid) (Ⅱ ) ,丁四醇 (erythritol) (Ⅲ ) ,汉黄芩素 7 O 葡萄糖苷 (wogonin 7 O glucoside) (Ⅳ )。 结论以上化合物均为首次从连翘中分离得到。用 2D NMR修正了文献中化合物Ⅰ部分碳信号归属错误
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| 关 键 词： | 连翘 化学成分 结构鉴定 |
| 文章编号： | 1006-2858(2003)02-0101-03 |
| 修稿时间： | 2002年7月4日 |
Study on the chemical constituents of the fruits of Forsythia suspensa(Thunb.) Vahl |
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| LIU Yue,SONG Shao-jiang,XU Sui-xu,FU Xiao-hui.Study on the chemical constituents of the fruits of Forsythia suspensa(Thunb.) Vahl[J].Journal of Shenyang Pharmaceutical University,2003,20(2):101-103. |
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| Authors: | LIU Yue SONG Shao-jiang XU Sui-xu FU Xiao-hui |
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| Abstract: | Objective To study the chemical constituents of Forsythia suspensa(Thunb.)Vahl.Methods Separation by column chromatography on silica gel,identification by physico-chemical characters and spectroscopic methods (IR?NMR,ESI-MS).Results Four compounds were isolated from the fruits of Forsythia suspensa(Thunb.)Vahl.The structures of the compounds were determined as isolariciresinol (Ⅰ),succinic acid (Ⅱ),erythritol (Ⅲ) and wogonin-7-O-glucoside (Ⅳ).Conclusions Compound Ⅰ,Ⅱ,Ⅲ and Ⅳ are firstly isolated from the fruits of Forsythia suspensa(Thunb.) Vahl.The 13C-NMR data of Compound Ⅰ are corrected by the 2D-NMR spectroscopic methods. |
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| Keywords: | Forsythia suspensa(Thunb )Vahl chemical constituents structure identification |
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