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苦参合剂对隐孢子虫病儿童免疫功能的影响
引用本文:崔巍,梁瑞文,王尊哲. 苦参合剂对隐孢子虫病儿童免疫功能的影响[J]. 中国病原生物学杂志, 2001, 14(1): 17-19
作者姓名:崔巍  梁瑞文  王尊哲
作者单位:潍坊医学院人体寄生虫学教研室,
摘    要:目的 观察苦参合剂对隐孢子虫病儿童免疫功能的影响。方法 用ABC法和3H-TdR掺入法检测T淋巴细胞亚群及淋巴细胞转化率,用单向琼脂扩散法检测免疫球蛋白,对隐孢子虫病儿童苦参合剂治疗前后的免疫功能进行测定。结果 患儿Tcell、Th值降低,淋巴细胞转化受抑,IgG升高。苦参合剂治疗后,临床腹泻症状消失,排虫转阴。Tcell、Th淋巴细胞转化值显著升高。结论 苦参合剂对隐孢子虫的感染有较好的驱虫与增强患儿细胞免疫力的作用。

关 键 词:苦参合剂; 隐孢子虫病; T淋巴细胞亚群;淋巴细胞转化
文章编号:1001-6627(2001)01-0017-03
修稿时间:1999-12-28

EFFECT OF RADIX SOPHORAEFLAVESCENTIS MIXTURE ON THE IMMUNE FUNCTION OF CRYPTOSPORIDIOSIS KIDS
CUI Wei,LIANG Rui-wen,WANG Zun-zhe. EFFECT OF RADIX SOPHORAEFLAVESCENTIS MIXTURE ON THE IMMUNE FUNCTION OF CRYPTOSPORIDIOSIS KIDS[J]. Journal of Pathogen Biology, 2001, 14(1): 17-19
Authors:CUI Wei  LIANG Rui-wen  WANG Zun-zhe
Abstract:Objective To observe the effect of Radix Sophorae Flavescentis mixture on the immune function of cryptosporidiosis kids. Methods Before and after treatment of Radix Sophorae Flavescentis mixture, the immune functions of the cryptosporidiosis patients were compared by measuring T lymphocyte subunits and lymphocytic transformation rate with methods of ABC and 3H TdR Incorporation and measuring the immunoglobin with method of employed one way argar diffusion. Results The number of T cell and Th decreased and the lymphocytes were inhibited and IgG value elevated in patients. After treatment of Radix Sophorae Flavescentis mixture, diarrehea in clinic disappeared and the test of excrement became negative. The number of T cell and Th and lymphocyte transformation rate all elevated signifcantly. Conclusion Radix Sophorae Flavescentis mixture has a better effect of dispersing cryptosporidium on its infection and enhancing the cellular immunity.
Keywords:Radix sophorae flavescentis mixture  cryptosporidiosis  T lymphocyte subunit  lymphocytic transformation
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