并发全身炎症反应综合征的经皮肾镜超声碎石术患者危险因素评估

目的探讨经皮肾镜超声碎石患者术后并发全身炎症反应综合征（systemic inflammatory response syndrome,SIRS）的危险因素。方法280例经皮肾镜超声碎石术后患者,分为并发SIRS组（27例）与非SIRS组（253例）,观察两组并发症、二次感染、血小板减少和C反应蛋白增高发生率。结果SIRS组术后平均住院（14.0±1.5）d,明显长于非SIRS组的（10.0±1.4）d SIRS组并发症、二次感染、PLT减少、CRP增高发生率分别为29.6%,11.1%,14.8%和29.6%,非SIRS组分别为2.4%,0.8%,0.8%和2.0%,组间比较均有显著性差异（P〈0.01）。结论经皮肾镜超声碎石术后并发SIRS患者较不并发SIRS的患者发生并发症、二次感染、血小板减少及C反应蛋白增高等机体损害的危险性高。

Risk Assessment of Systemic Inflammatory Response Syndrome for Patients Underwent Percutaneous Nephroscope Ultrasonic Lithotripsy

Objective To assess the risk of systemic inflammatory response syndrome （SIRS） for pa- nents who underwent percutaneous nephroscope ultrasonic lithotripsy （PNUL）. Methods 280 patients with kidney calculi or upper ureteric calculi were treated by PNUL. 280 cases were divided into SIRS group （n = 27） and non-SIRS group （ n = 253 ） according to complicate SIRS or not. The incidence rate of complication, seconda- ry infection, platelet reduction, and C-reactive protein elevation were compared between two groups. Results The hospital stay of SIRS group was （ 14.0 ± 1.5 ） days, and was obviously longer than （ 10.0 ±1. 4 ） days of non-SIRS group （ P 〈 O. O1 ）. The incidence rate of complication, secondary infection, platelet reduction and C- reactive protein elevation were 29.6%, 11.1%, 14.8% and 29.6% in SIRS group, and 2.4%, 0.8%, 0.8% and 2.0% in non-SIRS group, respectively. There was significant difference between two groups（P 〈 0.05 ）. Conclusion For PNUL patients, the risk of complication, secondary infection, platelet reduction and C-reac- tive protein elevation were higher in SIRS patients than that of non-SIRS patients.