恶性肿瘤并肺栓塞198例临床分析

目的探讨恶性肿瘤并肺栓塞的临床表现、病因及治疗转归。方法回顾性分析198例恶性肿瘤并肺栓塞患者的临床资料。结果198例患者中,128例（64.6%）为恶性肿瘤术后1个月内并肺栓塞;58例（29.3%）在肿瘤化、放疗期间或化、放疗结束后并肺栓塞;12例（6.1%）以肺栓塞为首发症状就诊,进一步检查发现恶性肿瘤。接受治疗的171例患者中,显效13例,有效123例,无效3例,恶化（死亡）32例。结论恶性肿瘤并肺栓塞临床表现复杂多样。对己发生肺栓塞患者应尽快诊断,积极救治;对手术、化疗、放疗或疾病进展可能导致血液高凝状态患者及早进行抗凝治疗,预防肺栓塞的发生。

Clinical Analysis of Pulmonary Embolism in Malignant Tumors of 198 Cases

Objective To explore the clinical manifestation,cause and treatment outcome of pulmonary embolism in patients with malignant tumors.Methods Retrospective analysis the clinical data of 198 cases in patients of pulmonary embolism with malignant tumors.Results Among 198 cases,128 cases（64.6%） of pulmonary embolism happened in 1 month postoperative malignant tumors resection.58 cases（29.3%） of pulmonary embolism happened during the period of chemoradiotherapy or after the end of chemoradiotherapy.12 cases（6.1%） the symptom of pulmonary embolism were occurred firstly for treatment,then malignant tumor revealed by further examination.Among 171 cases accepted treatment,13 cases significant effective,123 cases effective,3 cases ineffective,32 cases progressed（deaths）.Conclusion The clinical manifestations of pulmonary embolism with malignant tumor is complex and diverse,we should diagnose and treat those patients as soon as possible when pulmonary embolism had happened.Right there,operation,radiotherapy,chemotherapy and disease progression may lead to high blood coagulation status of patients,anticoagulant therapy should be applied earlier to prevent the occurrence of pulmonary embolism.