Dukes B期结直肠癌根治术后复发转移分析

目的探讨Dukes B期结直肠癌根治术后复发转移相关的临床病理因素。方法应用单因素分析法,回顾性分析1990-1999年265例Dukes B期结直肠癌根治术病例的临床病理因素。结果单因素分析显示,Dukes B期大肠癌的预后与肿瘤部位有关,直肠癌术后更易发生复发转移,特别是局部复发。而性别、年龄、病程、大体类型、肿瘤大小、组织学类型、分化程度、肠壁浸润深度与术后复发转移无关。结论Dukes B期的直肠癌患者术后局部复发的风险较大。

Analysis of recurrence of Dukes B colorectal cancer following radical surgery

Objective To investigate the clinicopathologic factors leading to recurrence of Dukes B (T_ 3-4 N_0M_0) colorectal cancer following radical surgery. Methods Clinicalpathological factors leading to recurrence in 265 cases with colorectal cancer at Dukes B treated with radical surgery from 1990 to 1999 were retrospectively analyzed by using univariate method. There were 220 cases without recurrence and 45 with recurrence. Results Univariate analysis showed that prognosis of colorectal cancer at Dukes B was significantly associated with site of tumor. Tumor recurrence and metastasis, especially local metastasis, could easily occur after surgery for rectal cancer. Yet, age, gender, symptom duration, gross findings, histological differentiation, tumor size and depth of bowel wall invasion were not associated with tumor recurrence. Conclusion Cases with rectal cancer at stage of Dukes B have additional risks for postoperative local recurrence.