颈动脉粥样硬化斑块类型与脑梗塞的相关性研究

目的:探讨脑梗塞与颈动脉粥样斑块硬化之间的关系,了解颈动脉彩色多普勒超声检查预测脑梗塞的作用。方法:对脑梗塞组(100例)患者和非脑梗塞对照组(100例)患者进行颈动脉彩色多普勒超声检查,分析脑梗塞与颈动脉粥样硬化斑块之间的关系。结果:脑梗塞组颈动脉粥样硬化斑块检出率为83%(83/100),显著高于对照组的斑块检出率19%(P0.01)。脑梗塞组的颈动脉软斑(26%:5%,P0.05)及混合斑检出率(44%:1%,P0.01)显著高于对照组。重型脑梗塞的颈动脉软斑(57.1%:17.1%,P0.05)及混合斑检出率(95.2%:2.9%,P0.01)显著高于轻型脑梗塞。结论:脑梗塞发病与颈动脉粥样硬化斑块相关。脑梗塞病情的轻、重在一定程度上与硬化斑块的性质有关。颈动脉彩色多普勒超声检查对脑梗塞预测有重要临床意义。

Correlation between carotid artery atherosclerlotic plaque and cerebral infarction

Objective：To investigate the relationship between cerebral infarction and carotid atherosclerlotic artery plague,and determine the value of color Doppler ultrasonography for carotid artery in prediction of cerebral infarction.Methods：Patients in cerebral infarction group（n=100） and control group without cerebral infarction（n=100） received color Doppler ultrasonography for carotid artery.The relationship between cerebral infarction and carotid artery atherosclerlotic plague was analyzed.Results：In cerebral infarction group,the detection rate of carotid artery atherosclerlotic plague was 83%（83/100）,which was significantly higher than that of control group（19%,P〈0.01）;the detection rate of atherosclerlotic soft plague（26% vs.5%,P〈0.05） and atherosclerlotic mixed plague（44% vs.1%,P〈0.01） were also significantly higher than those of control group.The detection rates of soft plague（57.1% vs.17.1%,P〈0.05） and mixed plague（95.2% vs.2.9%,P〈0.01） in patients with severe cerebral infarction were significantly higher than those of patients with mild cerebral infarction.Conclusion：The incidence of cerebral infarction is related with carotid artery atherosclerlotic plaque.The severity of cerebral infarction is related with property of atherosclerlotic plaque to some extent.Color Doppler ultrasonography for carotid artery has important clinical significance in prediction of cerebral infarction.