| 复方苦参注射液对直肠癌患者CEA、CA199及生活质量的影响 |
| |
| 引用本文： | 王奕,唐求,龙志雄. 复方苦参注射液对直肠癌患者CEA、CA199及生活质量的影响[J]. 中国肿瘤临床与康复, 2011, 0(3): 285-286 |
| |
| 作者姓名： | 王奕 唐求 龙志雄 |
| |
| 作者单位： | 武汉市中心医院;武汉市第五医院; |
| |
| 摘 要： | 目的探讨复方苦参注射液对直肠癌患者肿瘤标志物CEA、CA199及生活质量的影响。方法将58例直肠癌患者随机分成两组,治疗组29例应用FOLFOX-4方案加复方苦参注射液静脉滴注,对照组29例应用FOLFOX-4方案。比较直肠癌患者使用复方苦参注射液前后CEA、CA199检测值及生活质量评分的变化。结果治疗组优于对照组,治疗组在化疗结束后第12天CEA为(4.23±0.50)ng/L,CA199为(18.11±3.14)ng/ml,均低于化疗结束后第一天CEA(5.34±0.48)ng/L,CA199(26.31±2.36)ng/L,但两者差异无显著性(P>0.05);对照组在化疗结束后第1天和第12天CEA和CA199的值变化不大,差异亦无显著性。治疗组Karnofsky降低率(17.2%)明显低于对照组(48.3%),两者差异有显著性(P<0.05)。结论复方苦参注射液可降低直肠癌康复期患者CEA及CA199水平,但差异无显著性。复方苦参注射液治疗能提高KPS得分,有效改善生存质量,差异有显著性。
|
| 关 键 词： | 复方苦参注射液 直肠肿瘤 肿瘤标志物 生存质量 |
The effect of Yan-shu Injection on tumor markers(CEA,CA199)and quality of life in rectal cancer patients |
| |
| WANG Yi ,TANG Qiu,LONG Zhi-xiong. The effect of Yan-shu Injection on tumor markers(CEA,CA199)and quality of life in rectal cancer patients[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2011, 0(3): 285-286 |
| |
| Authors: | WANG Yi TANG Qiu LONG Zhi-xiong |
| |
| Affiliation: | WANG Yi 1,TANG Qiu1,LONG Zhi-xiong2(1.Wuhan Central Hospital,Wuhan 430014,China,2.The Fifth Municipal Hospital of Wuhan,China) |
| |
| Abstract: | Objective To study the effect of Yan-shu Injection on tumor markers(CEA,CA199)and quality of life in rectal cancer patients.Methods A total of 58 patients with rectal cancer were enrolled,29 were randomized to treatment group(chemotherapy plus Yan-shu) and 29 to control group(chemotherapy).The regimen of FOLFOX-4 was taken for chemotherapy.The variation of tumor markers(CEA,CA199) in peripheral blood and quality of life before and after therapy with Yan-shu Injection were observed.Results The levels of CEA(... |
| |
| Keywords: | Yan-shu Injection Rectal neoplasms Tumor markers Quality of life |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
