江苏省部分地区中华按蚊对溴氰菊酯和氟氯氰菊酯的敏感性调查

目的了解江苏省部分疟区中华按蚊对溴氰菊酯和氟氯氰菊酯的敏感性。方法采用WHO推荐的接触筒强迫接触法，观察接触10、15、20、30、40、50、60min的蚊虫击倒数和24h后的死亡率。结果盱眙、泗洪、睢宁、宜兴4个县（市）中华按蚊接触0．05％溴氰菊酯60min时的击倒率分别为67．37％、64．00％、71．43％和78．40％，24h后的死亡率分别为68．42％、68．00％、72．53％和76．80％，4个县（市）的中华按蚊对溴氰菊酯的抗性评价均为R级。盱眙、泗洪、睢宁、宜兴4个县（市）中华按蚊接触0．15％氟氯氰菊酯60min时的击倒率分别为84．13％、91．76％、89．80％和100％，24h后的死亡率分别为85．71％、91．76％、93．88％和100％，宜兴地区的中华按蚊对氟氯氰菊酯抗性评价为S级，其他3个县（市）的中华按蚊对氟氯氰菊酯抗性评价为M级。结论江苏省部分疟区中华按蚊已对溴氰菊酯产生高度抗性，对氟氯氰菊酯已产生初步抗性。今后，在媒介防制上应采取综合治理措施，以防止抗性产生。

Sensitivity of Anopheles sinensis to deltamethrin and cyfluthrin in part areas of Jiangsu province

Objective To observe the sensitivity of Anopheles sinensis to dehamethrin and cyfluthrin in malaria epidemic areas of Jiangsu province. Methods The adult mosquito test kit was used in this study recommended by WHO. The quantity of adult mosquitoes knocked down by dehamethrin and cyiluthrin was counted after exposure 10 min, 15 min, 20 min, 30 min, 40 min, 50 min and 60 min, and its mortality after treatment for 24 h was recorded. Results The knock down rates of An.sinensis to dehamethrin in Xuyi, Sihong, Suining, and Yixing county （city） were 67.37%, 64.00%, 71.43%, and 78.40% at 60 min after treatment, respectively, and the mortalities at 24 h after treatment were 68.42%, 68.00%, 72.53% and 76.80%, respectively. The resistance level of the An.sinensis to deltamethrin in four areas investigated was evaluated as ＂R＂. The knock down rate of An.sinensis to cyfluthrin were 84.13%, 91.76%, 89.80% and 100% at 60 min after treatment in Xuyi, Sihong, Suining, and Yixing county（city）, respectively. The mortalities at 24 h after treatment were 85.71%, 91.76%, 93.88% and 100%, respectively. The resistance level of An.sinensis to cyfluthrin in Yixing area was assessed as ＂S＂, and ＂M＂ level in other three counties. Conclusion An.sinensis has high resistance to dehamethrin and low resistance to cyfluthrin in parts of malaria epidemic areas. In order to prevent development of resistance, the integrated management measures should be taken in the future.