不同时段选择性动脉溶栓治疗急性脑梗死的临床研究

目的：探讨病程超过6小时的脑梗死动脉溶栓治疗的可行性，方法：44例脑梗死患者按病程分为A组（病程≤6h)和B组（病程6－24h)，两组均接受选择性动脉溶栓治疗。结果：对两组间的血管再通率，治疗前后神经功能缺损积分差值，病后90天的巴氏指数，出血转化率和溶栓治疗中发生血管再通的时间进行比较，均无显著性差异，结论：部分脑梗死患者选择性动脉溶栓治疗时间窗可以延长至6小时以后，且仍可以取得较高血管再通率和较好的临床疗效。

Stady on Selective Intra-arterial Thrombolytic Therapy of Different Time Course in Patients with Acute Cerebral Infarction

Objective To investigate the practicability in patients with acute cerebral infarction after 6 hours of stroke onset who received intra-arterial thrombolytic therapy.Methods 44 cases were divided into two groups(A and B)according to course of time within 6 hours and from 6 to 24 hours of stroke onset for received intra-arterial thombolytic therapy.Results There were no significant differences in recanalization rate,clinical outcome,cerebral hemorrhage inciednce and reperfusive time of occluded artery between A and B.Conclutions Part of the cases with cerebral infarction after 6 hours of stroke onset can benefit from intra-arterial thrombolytic therapy?