| p16,E6/E7蛋白与宫颈癌及癌前病变相关性的研究进展 |
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| 作者单位： | 山西医科大学第一临床医学院;山西医科大学第一医院妇科 |
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| 摘 要： | 宫颈癌是女性最常见的、发病率较高、但完全可以通过筛查早期发现并进行有效防治的恶性肿瘤。在宫颈病变中,高危型HPV病毒的持续感染是导致其发生发展的明确病因,近年来,p16,HPV E6/E7蛋白在明确宫颈病变的发病机制、诊断、临床分流等方面的作用备受关注。
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| 关 键 词： | 宫颈病变 P16 HPV E6/E7 免疫组织化学分析 |
Research progress in correlation between p16, E6/E7 proteins and cervical cancer and precancerous lesions |
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| Affiliation: | (First Clinical Medical College,First Hospital,Shanxi Medical University,Taiyuan 030000,China;Department of Gynecology,First Hospital,Shanxi Medical University,Taiyuan 030000,China) |
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| Abstract: | Cervical cancer is the most common malignant tumor in women with high incidence,but can be detected early and effectively prevented by screening.In cervical lesions,the persistent infection of high-risk HPV virus is a clear cause of its development.In recent years,the role of P16 and HPV E6/E7 proteins in the pathogenesis,diagnosis and clinical shunt of cervical lesions has attracted much attention. |
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| Keywords: | cervical lesions p16 HPV E6/E7 immunohistochemical analysis |
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