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肺动脉栓塞指数的研究进展
作者姓名:周果  伍慧杰  孙美琪  郝倩文  张薇
作者单位:哈尔滨医科大学附属第一医院呼吸内科
摘    要:急性肺栓塞(acute pulmonary embolism,APE)是以各种栓子阻塞肺动脉及其分支为其发病原因的一组疾病或综合征,也是临床病死率较高的疾病之一。肺栓塞的诊断方法有螺旋CT、放射性核素肺通气/血流灌注(V/Q)显像、磁共振成像和磁共振肺动脉造影、肺动脉造影。螺旋CT中的多排螺旋CT肺动脉造影诊断肺栓塞的敏感性及特异性较高,因此广泛应用于临床。肺动脉栓塞指数(pulmonary artery obstruction index,PAOI)是通过螺旋CT的多排螺旋CT肺动脉造影进行计算的一种临床指标。本文就PAOI与APE危险分层,PaO2,PaCO2,P(A-a)O2,SaO2,RVd/LVd,MPAd,SVCd,肺动脉高压,D-二聚体等的相关性研究现状作一综述。

关 键 词:肺栓塞  肺动脉栓塞指数  危险分层

Research progress of pulmonary embolism index
Authors:ZHOU Guo  WU Huijie  SUN Meiqi  HAO Qianwen  ZHANG Wei
Institution:(Department of Respiratory Medicine,First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)
Abstract:Acute pulmonary embolism(APE) is a group of diseases or syndromes caused by various emboli blocking pulmonary artery and its branches.The Diagnostic methods of pulmonary embolism include helical CT,radionuclide pulmonary ventilation/blood perfusion(V/Q) imaging,magnetic resonance imaging and magnetic resonance pulmonary arteriography,pulmonary arteriography.Helical CT is widely used in clinical practice because of its high sensitivity and specificity in the diagnosis of pulmonary embolism.Pulmonary embolism index is a clinical index calculated by helical CT pulmonary angiography.The article reviews the current research on the correlation between PAOI with APE risk stratification,PaO2,PaCO2,P(A-a)O2,SaO2,RVd/LVd,MPAd,SVCd,pulmonary hypertension,D-dimer.
Keywords:pulmonary embolism  pulmonary embolism index  risk stratification
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