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金柴小儿肺炎颗粒药效学研究
引用本文:孙玉华,黄华,杨丽丽,哈木拉提,崔晓兰,刘发. 金柴小儿肺炎颗粒药效学研究[J]. 中成药, 2005, 27(2): 191-194
作者姓名:孙玉华  黄华  杨丽丽  哈木拉提  崔晓兰  刘发
作者单位:1. 新疆维吾尔自治区药物研究所,新疆,乌鲁木齐,830002
2. 中国中医研究院中药研究所,北京,100700
摘    要:目的:研究JCG体内外抗菌和抗病毒作用.方法:用体外抗菌及病原菌感染小鼠造模检测抗菌作用;用细胞培养和小鼠流感病毒性肺炎模型研究对病毒的抑制作用等;小鼠扭体模型研究镇痛;小鼠气管酚红排泌量模型研究祛痰.结果:体内外试验表明JCG对肺炎球菌有较好的抑菌和杀菌作用.对呼吸道多种病毒所致细胞病变均有明显抑制作用.三剂量使流感病毒致小鼠肺炎模型的肺指数值、肺病变程度明显轻于病毒对照组(P<0.05).结论:JCG对呼吸道常见感染菌、病毒有抑杀作用,并有解热、止痛、祛痰、镇咳作用.

关 键 词:金柴小儿肺炎颗粒(贯叶金丝桃、柴胡、黄芩等)(JCG)  降温  镇痛  祛痰  镇咳
文章编号:1001-1528(2005)02-0191-04

Pharmocodynamics of Jinchai Xiaoer Feiyan Granule
SUN Yu-hua,HUANG Hua,YANG Li-li,Hamulati,CUI Xiao-lan,LIU Fa. Pharmocodynamics of Jinchai Xiaoer Feiyan Granule[J]. Chinese Traditional Patent Medicine, 2005, 27(2): 191-194
Authors:SUN Yu-hua  HUANG Hua  YANG Li-li  Hamulati  CUI Xiao-lan  LIU Fa
Abstract:AIM: To observe the effect of JXFG(Radix Bupleuri, Radix Seutellariae, etc.) on anti-bacteria and anti-virus actions. METHODS: Tube culture was used to study the anti-bacteria effect of JXFG. The model of mouse infected by pathogenic bacteria was established to examine the anti-bacteria effects of JXFG. RESULTS: The anti-bacteria experiments of JXFG in vitro and vivo showed that JXFG had strong an effect on inhibiting pneumococcus. It had significant the effect of inhibiting cells pathologic change induced by varies varies common respiratory virus. CONCLUSION: JXFG hax the effect of inhibiting common bacteria and virus of respiratory tract, and has the effect of resolving heat, relieving pain, analgesia, removing phlegm and relieving cough.
Keywords:Jinchai Xiaoer Feiyan Granule(JXFG)  cooling  analgesia  removing phlegm  relieving cough  
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