蚕豆病60例临床分析

目的探讨蚕豆病的发病因素及诊疗措施。方法回顾性总结60例蚕豆病的临床资料,分析其发病机制,治疗措施及预后。结果蚕豆病4岁以下患者占70.15%,病死率为0.17%;所有病例葡萄糖-6磷-酸脱氢酶(G-6-PD)活性均降低。结论蚕豆病是一种遗传性疾病,主要是由于G-6-PD缺陷者进食蚕豆而引起的急性溶血性贫血,为非自限性,及时输注新鲜血液、激素及碱化尿液等综合措施,是有效的治疗方法。

Clinical Analysis on 60 Fabism Cases

Objective To investigate the incidence factors and therapeutic approaches of fabism.Method The clinical materials of sixty fabism patients were retrospectively summarized.The incidence mechanisms,therapeutic approaches and prognosis were analysed.Results 70.15% of fabism patients were under four years old in age,death rate was 0.17%,and G-6-PD activity was decreased in all the cases.Conclusion Fabism,a kind of hereditary disease,is an acute hemolytic anemia in G-6-PD defective patients induced by eating broad bean(Vicia faba).It is non-self limited,and timely input of fresh blood if necessary.Alkalizing urine,hormone and some other comprehensive approaches are the effective therapies.