床旁血液灌流抢救重度有机磷农药中毒疗效观察及护理

目的:探讨床旁血液灌流(HP)治疗重度有机磷农药中毒(AOPP)患者的疗效和护理。方法:将104例AOPP患者随机分为灌流组50例和非灌流组54例,非灌流组给予常规洗胃、导泻、输液及氯磷定、阿托品治疗,灌流组在此基础上给予HP。结果:灌流组治愈率、中间综合征发生率、昏迷时间、血胆碱酯酶恢复时间和阿托品用量与非灌流组相比有显著性差异(P<0.05,P<0.01)。结论:HP能迅速清除体内毒物,明显缩短病程,减少并发症,提高AOPP的治愈率。

Clinical observation and nursing of bedside hemoperfusion on acute severe organophosphorus pesticide poisoning

Objective: To explore the clinical effects and nursing of bedside hemoperfusion therapy on acute severe organophosphorus pesticide poisoning(AOPP). Methods:104 patients with severe AOPP were divided into hemoperfusion group(50 cases) and non-hemoperfusion group(54 cases).The non-hemoperfusion were given conventional treatment including gastrolavage,purgation,fluid infusion,atropine and pralidoxime chloride.On the basis of the conventionzl treatment,the hemoperfusion group were given additional hemoperfusion therapy.Results:There were significant differences in cure rate,incidence of intermediate syndrome,coma duration,serum cholinesterase recovery time and atropine dosage between two groups(P<0.05,P<0.01).Conclusion:Hemoperfusion can clear organophosphorus pesticide rapidly,shorten duration of illness,reduce complication and improve the cure rate of severe AOPP.