| 逐瘀生骨汤对老年髋关节置换术后股骨假体周围早期骨溶解影响的临床研究 |
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| 引用本文： | 王竞超,王凌椿,叶博闻,丁盛,欧阳桂林.逐瘀生骨汤对老年髋关节置换术后股骨假体周围早期骨溶解影响的临床研究[J].上海中医药杂志,2017,51(3):48-50. |
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| 作者姓名： | 王竞超 王凌椿 叶博闻 丁盛 欧阳桂林 |
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| 作者单位： | 上海市长宁区光华中西医结合医院关节外科,上海,200052,上海市长宁区光华中西医结合医院关节外科,上海,200052,上海市长宁区光华中西医结合医院关节外科,上海,200052,上海市长宁区光华中西医结合医院关节外科,上海,200052,上海市长宁区光华中西医结合医院关节外科,上海,200052 |
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| 基金项目： | 上海市长宁区科委中医引导项目(16401930400) |
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| 摘 要： | 目的探讨逐瘀生骨汤对老年髋关节置换术(THA)后股骨假体周围早期骨溶解的影响。方法将60例行THA的老年患者随机分为联合组和对照组,各30例。对照组术后给予阿伦膦酸钠口服,联合组在此基础上加用逐瘀生骨汤,疗程均为6个月。观察两组患者假体周围骨密度值变化、骨代谢状况及炎性因子变化情况。结果(1)治疗后,对照组ROI 1~7区骨密度值均显著下降(P0.05),联合组ROI 7区骨密度值显著下降(P0.05);除ROI 4区外,联合组各区骨密度值均显著高于对照组(P0.05)。(2)治疗后,两组TPⅠNP、CTX-β均较治疗前显著下降(P0.05),且联合组明显低于对照组(P0.05)。(3)治疗后,两组IL-6、CRP、TNF-α水平均较治疗前显著下降(P0.05),且联合组低于对照组(P0.05)。结论逐瘀生骨汤可有效抑制老年THA术后炎性反应,预防股骨假体周围骨量流失,延缓骨溶解。
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| 关 键 词： | 髋关节置换术 骨溶解 逐瘀生骨汤 老年 |
| 收稿时间： | 2016/11/15 0:00:00 |
Clinical study on the effects of Zhuyu Shenggu Decoction on early osteolysis of periprosthetic femoral after total hip replacement in elderly patients |
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| WANG Jing-chao,WANG Ling-chun,YE Bo-wen,DING Sheng and OUYANG Gui-lin.Clinical study on the effects of Zhuyu Shenggu Decoction on early osteolysis of periprosthetic femoral after total hip replacement in elderly patients[J].Shanghai Journal of Traditional Chinese Medicine,2017,51(3):48-50. |
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| Authors: | WANG Jing-chao WANG Ling-chun YE Bo-wen DING Sheng and OUYANG Gui-lin |
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| Institution: | Joint Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Changning District, Shanghai, 200052,Joint Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Changning District, Shanghai, 200052,Joint Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Changning District, Shanghai, 200052,Joint Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Changning District, Shanghai, 200052 and Joint Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Changning District, Shanghai, 200052 |
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