妊娠期肝内胆汁淤积症的处理与妊娠结局

目的:探讨妊娠期肝内胆汁淤积症的处理以及对妊娠结局的影响,以防范医疗风险.方法:总结分析典型病例的诊治经过与妊娠结局,并复习文献.结果:例1在引产待产过程中胎儿死亡,再次妊娠时发病早、病情重,药物及综合治疗可延长孕龄,仍发生早产、胎膜早破和胎粪污染,需及时剖腹产.结论:本病医疗风险极大,无有效治疗方法来控制病情发展,掌握终止妊娠的时机和方法最关键.母亲预后好,围产儿发病率和死亡率高.

The therapy of intrahepatic cholestasis of pregnancy and pregnant outcome

Objective: To investigate the therapy of Intrahepatic Cholestasis of Pregnancy and effects on pregnancy, and prevent the risk of medicine. Method: Analyze diagnosis progress and pregnant outcome of typical case and go over the literatures. Result: One case in which fetus died during the progress of induced labor, the onset of illness of next pregnancy is earlier, and serious, drug and colligation therapy can not only elongate the gestational age but also lead to premature birth, premature rupture of membranes and meconium contamination, and need to have cesare-an. Conclusion: This disease have a high risk of medicine and have no good method to control the development of condition, so it is critical to grasp the time and way of pregnancy termination. Mother have a good prognosis, but the incidence rate and mortality rate is high of perinatal fetus.