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动脉灌注化疗药物和免疫制剂在治疗晚期胃肠道肿瘤中的应用
引用本文:何建苗,蒲永东,朱志东,杨波,董立国. 动脉灌注化疗药物和免疫制剂在治疗晚期胃肠道肿瘤中的应用[J]. 解放军医学杂志, 2002, 27(3): 259-260
作者姓名:何建苗  蒲永东  朱志东  杨波  董立国
作者单位:100091,北京,解放军第309医院
摘    要:为评价动脉内灌注化疗药物和免疫制剂对治疗晚期胃肠道肿瘤的临床疗效,将86例不能切除的胃肠道肿瘤随机分成两组,A组46例,行动脉灌注化疗同时进行免疫治疗,B组40例,单纯动脉灌注化疗。结果肿瘤治疗有效率(CR+PR)A组82.6%,B组52.5%;0.5、1和2年生存率,A组分别为100%、82.6%和56.5%,B组分别为100%、65%和42.5%。表明动脉内灌注化疗药物和免疫制剂治疗能有效提高晚期胃道肿瘤的治疗效果。

关 键 词:动脉内灌注化疗 免疫治疗 晚期胃肠道肿瘤
修稿时间:2001-07-05

CLINICAL STUDY ON THE EFFECT OF INTRA-ARTERIAL INFUSION CHEMOTHERAPEUTIC MEDICINE AND IMMUNIZATOR OF LATER GASTRO-INTESTINAL CARCINOMA
He Jianmiao,Pu Yongdong,Zhu Zhidong et al . Hospital of PLA,Beijing. CLINICAL STUDY ON THE EFFECT OF INTRA-ARTERIAL INFUSION CHEMOTHERAPEUTIC MEDICINE AND IMMUNIZATOR OF LATER GASTRO-INTESTINAL CARCINOMA[J]. Medical Journal of Chinese People's Liberation Army, 2002, 27(3): 259-260
Authors:He Jianmiao  Pu Yongdong  Zhu Zhidong et al . Hospital of PLA  Beijing
Affiliation:He Jianmiao,Pu Yongdong,Zhu Zhidong et al . 309 Hospital of PLA,Beijing 100091
Abstract:To evaluate the effect of intra arterial infusion chemotherapeutic medicine and immunizator in treatment of later gastro intestinal carcinoma, 86 cases suffering from irremovable gastro intestinal carcinoma were divided into treatment group(group A) and control group (group B). 46 cases in group A were treated with intra arterial chemo immunotherapy, 40 cases in group B were treated only with chemotherapy. Effective rates of group A and group B were 82 6% and 52 5% ( P <0 01) .The survival rate of 0 5, 1 and 2 years in group A was 100%, 82 6%, 56 5%, and in group B was 100%, 65%, 42 5%. Intra arterial infusion chemotherapeutic medicine and immunizator can increase the therapeutic effect of later gastro intestinal carcinoma .
Keywords:digestive system neoplasms  intra arterial infusion chemotherapy  immunotherapy
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