Dissemination of Carbapenemase-Producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania |
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| Authors: | Laurent Dortet Mirela Flonta Yves-Marie Boudehen Elodie Creton Sandrine Bernabeu Ana?s Vogel Thierry Naas |
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| Institution: | aBacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France;bParis-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France;cAssociated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France;dClinical Hospital of Infectious Diseases, Microbiology Laboratory, Cluj-Napoca, Romania |
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| Abstract: | Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing Pseudomonas aeruginosa isolates were recovered from patients hospitalized between August 2011 and March 2013 at the Hospital of Infectious Disease, Cluj-Napoca, Romania. One KPC-, nine NDM-1-, four OXA-48-, and one VIM-4-producing Enterobacteriaceae isolates along with 11 VIM-2-producing and one IMP-13-producing P. aeruginosa isolates were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were associated with other resistance determinants, including extended-spectrum β-lactamases and RmtC methylases. |
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