Aggressive B-cell lymphoma induced by Epstein-Barr virus infection in erythrodermic cutaneous T-cell lymphoma |
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| Authors: | A KIKUCHI H ANZAI H KOSUGE W NAKA T NISHIKAWA |
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| Institution: | Department of Dermatology, Keio University School of Medicine, 35 Shianomachi. Shinjukiu. Tokyo 160. Japan |
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| Abstract: | The coexistence of two cutaneous non-Hodgkin's lymphomas of different lineage is rare. We report a patient with an indolent erythrodermic cutaneous T-cell lymphoma followed by an aggressive B-cell lymphoma. To our best knowledge, this is the first report describing Epstein-Barr virus-associated B-cell lymphoma in a patient with cutaneous T-cell lymphoma. We suggest that the long-standing cutaneous T-cell lymphoma, as well as the long-term chemotherapy, suppressed host immunity and caused reactivation of latent Epstein-Barr virus. |
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