Incidence of hepatitis B virus infection among an Italian military population: Evidence of low infection spread |
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| Authors: | R D'Amelio Dr T Stroffolini R Nisini P M Matricardi M Rapicetta E Spada A Napoli P Pasquini |
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| Institution: | (1) Laboratorio di Immunologia, Divisione Aerea, Studi, Ricerche e Sperimentazione, Aeronautica Militare, Rome, Italy;(2) Dipartimento di Medicina Sperimentale, Universita di Reggio Calabria, Catanzaro;(3) Laboratorio di Epidemiologia e di virologia, ISS, Rome, Italy;(4) Laboratorio di Epidemiologia, Istituto Superiore di Sanità, viale Regina Elena 299, I-00161 Rome, Italy |
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| Abstract: | In 1990, a prospective serological survey to estimate the rate of clinical and inapparent infection with hepatitis B virus was performed in a cohort of 1324 soldiers, 18–24 years old, during an eight month period in Italy. At the time of enrollment the prevalence of hepatitis B markers was 4.6% (0.7% subjects positive for hepatitis B surface antigen HBsAg], 3.0% positive for antibody to hepatitis B surface antigen anti-HBs], and 0.9% positive for antibody to hepatitis B core antigen anti-HBc] alone. Among the 1263 susceptible subjects who were followed-up, only 2 (0.24/100 person-years of exposure) had seroconversion for HBV markers, none of which was associated with clinical illness. Among the 9 subjects HBsAg-positive at the time of enrollment, 1 (11.2%) had lost HBsAg at the end of follow-up. These data show a low spread of HBV infection among Italian young generations. |
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| Keywords: | Hepatitis B Incidence Infection Italy |
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