| MRI结合数字化钼靶诊断乳腺癌的临床研究 |
| |
| 引用本文： | Fang Ye Mengsu Zeng Fuhua Yan Wei Feng Meiling Zhou Renchen Li Wenfang Chen. MRI结合数字化钼靶诊断乳腺癌的临床研究[J]. 中德临床肿瘤学杂志, 2008, 7(5): 286-291. DOI: 10.1007/s10330-008-0018-y |
| |
| 作者姓名： | Fang Ye Mengsu Zeng Fuhua Yan Wei Feng Meiling Zhou Renchen Li Wenfang Chen |
| |
| 作者单位： | Fang Ye（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Mengsu Zeng（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Fuhua Yan（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Wei Feng（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Meiling Zhou（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Renchen Li（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） Wenfang Chen（Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China） |
| |
| 摘 要： | ObjectiveTo compare the effectiveness of digital mammography and MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of the two.MethodsSixty-seven patients with surgery and pathology proved breast lesion (malignant,n＝32; benign,n＝46) underwent digital mammography and MRI,the pulse sequences included T1WI,T2Wl,diffuse weighted imaging (DWI),and dynamic contrast-enhanced MRI before surgery.Of the results of these two modalities,all lesions were classified into 5 groups according to BI-RADS classification,and the imaging findings were correlated to histopathology.The sensitivity and specificity of each modality as well as the combination of the two were calculated.ResultsOf these 78 breasts lesions,The sensitivity was 78.13%% (25/32) for digital mammography and 93.75% (30/32) for MRI (P＞0.05).The specificity was 73.91%% (34/46) and 89.13% (41/46) accordingly (P＜0.05),both of them showed statistical difference.The sensitivity and specificity was 98.63% and 97.16% respectively as these two modalities were used in combination.ConclusionDigital mammography in combination with MRI is helpful in the diagnosis of breast cancer,the sensitivity and specificity was enhanced when compared to that of single modality.
|
| 关 键 词： | magnetic resonance imaging breast neoplasms mammography 结合 数字化 钼靶 诊断乳腺癌 临床研究 digital mammography study Clinical breast cancer diagnosis single Digital used statistical difference sensitivity specificity modality histopathology lesions |
| 修稿时间： | 2008-01-30 |
Clinical study of digital mammography,contrast-enhanced MRI as well as their combination in the diagnosis of breast cancer |
| |
| Fang Ye,Mengsu Zeng,Fuhua Yan,Wei Feng,Meiling Zhou,Renchen Li,Wenfang Chen. Clinical study of digital mammography,contrast-enhanced MRI as well as their combination in the diagnosis of breast cancer[J]. The Chinese-German Journal of Clinical Oncology, 2008, 7(5): 286-291. DOI: 10.1007/s10330-008-0018-y |
| |
| Authors: | Fang Ye Mengsu Zeng Fuhua Yan Wei Feng Meiling Zhou Renchen Li Wenfang Chen |
| |
| Affiliation: | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China |
| |
| Abstract: | Objective:To compare the effectiveness of digital mammography and MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of the two.Methods:Sixty-seven patients with surgery and pathology proved breast lesion (malignant,n＝32; benign,n＝46) underwent digital mammography and MRI,the pulse sequences included T1WI,T2Wl,diffuse weighted imaging (DWI),and dynamic contrast-enhanced MRI before surgery.Of the results of these two modalities,all lesions were classified into 5 groups according to BI-RADS classification,and the imaging findings were correlated to histopathology.The sensitivity and specificity of each modality as well as the combination of the two were calculated.Results:Of these 78 breasts lesions,The sensitivity was 78.13%% (25/32) for digital mammography and 93.75% (30/32) for MRI (P＞0.05).The specificity was 73.91%% (34/46) and 89.13% (41/46) accordingly (P＜0.05),both of them showed statistical difference.The sensitivity and specificity was 98.63% and 97.16% respectively as these two modalities were used in combination.Conclusion:Digital mammography in combination with MRI is helpful in the diagnosis of breast cancer,the sensitivity and specificity was enhanced when compared to that of single modality. |
| |
| Keywords: | magnetic resonance imaging breast neoplasms mammography |
| 本文献已被 维普 万方数据 SpringerLink 等数据库收录！ |
|
