Questioning the efficacy of Fallopian tube sperm perfusion |
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Authors: | El Sadek MM; Amer MK; Abdel-Malak G |
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Institution: | Department of Obstetrics and Gynecology, Cairo University, Egypt. |
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Abstract: | The aim of this work was to compare the efficiency of standard intrauterine
insemination (IUI) and Fallopian tube sperm perfusion (FSP) in the
treatment of infertility. Ninety-six consecutive patients with infertility
in 100 cycles were included in the study. Those randomized to standard IUI
included 48 patients in 50 cycles 25 clomiphene citrate only and 25
clomiphene citrate/human menopausal gonadotrophin (HMG) cycles] (group I).
Patients subjected to FSP included 48 patients in 50 cycles (18 clomiphene
citrate only and 32 clomiphene citrate/HMG cycles) (group II). The overall
pregnancy rate per cycle (16% versus 18%) was not significantly different
in the two groups. The pregnancy rates were also similar in the two groups
when compared for the cause of infertility: ovulatory disorder 16.7% versus
16%, tubal impairment 10% versus 9.1%, cervical hostility (no pregnancy
occurred in this group) and unexplained infertility 21.4 % versus 25 %. The
overall pregnancy rate (for the two groups) appeared higher when clomiphene
citrate/HMG was used for ovulation induction (21.1%) than when clomiphene
citrate only was used (11.6%).
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