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Congenital pupillary-iris-lens membrane with goniodysgenesis (a new entity)
Authors:G W Cibis  J M Waeltermann  E Hurst  R C Tripathi  W Richardson
Affiliation:1. Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia;2. King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia;3. Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Abstract:We encountered two clinically similar but genetically unrelated cases of a disorder characterized by an unusual white pupillary-iris-lens membrane with extension to a prominent Schwalbe's line, the membranes were vascularized and their appearance changed over time. In both cases the abnormality was unilateral. Anomalous chamber angles were seen on gonioscopy. The clinical appearance is similar to a combination of iridogoniodysgenesis and pupillary membrane. However, our two cases are unique and fit into neither category. We postulate that this is a new entity consisting of an anomalous chamber angle and iris-lens membrane resulting from a localized iris (pupillary membrane), infarct with secondary neovascularization, during formation of the chamber angle.
Keywords:iridogoniodysgenesis  pupillary membrane  Rieger syndrome  secluded pupil
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