| 大叶香茶菜辛素的结构 |
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| 引用本文： | 程培元,许美娟,林永乐,石金城,徐光漪.大叶香茶菜辛素的结构[J].药学学报,1986,21(2):109-113. |
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| 作者姓名： | 程培元 许美娟 林永乐 石金城 徐光漪 |
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| 作者单位： | 南京药物研究所
(程培元，许美娟，林永乐，石金城)，上海医药工业研究院(徐光漪) |
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| 摘 要： | 从大叶香茶菜Rabdosia macrophylla(Migo)C.W.Wu et H.W.Li干叶中提取、分离得十五种成分,其中数种为具有抗肿瘤或细胞毒活性的二萜。本文报道另一种新二萜成分大叶香茶菜辛素(rabdophyllin H)的结构,并由X线单晶衍射方法证实。大叶香茶菜辛素对QGY-7703肝癌细胞具有抑制作用。
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| 关 键 词： | 大叶香茶菜 大叶香茶菜庚素 大叶香茶菜辛素 香茶菜甲素 冬凌草素 Isodnal Lasiodonin Lasiokaurin |
| 收稿时间： | 1985-01-04 |
STRUCTURE OF RABDOPHYLLIN H |
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| CHENG Pei-Yuan,XU Mei-Juan,LIN Yng-Le,SHI Jin-Cheng and XU Guang-Yi.STRUCTURE OF RABDOPHYLLIN H[J].Acta Pharmaceutica Sinica,1986,21(2):109-113. |
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| Authors: | CHENG Pei-Yuan XU Mei-Juan LIN Yng-Le SHI Jin-Cheng and XU Guang-Yi |
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| Abstract: | Fifteen components were isolated from the dry leaves of Rabdosia macrophylla. Six of them were found to be kaurene type diterpenoids and shown to have antitumor activities or cytotoxicity.
This paper reports the structure of a new kaurane type diterpenoid named rabdophyllin H. This compound showed cytotoxicity against QGY- 7703 Heptoma cells. |
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| Keywords: | Rabdosia macrophylla Rabdophyllin G Rabdophyllin H Amethystoidin A Oridonin Isodonal Lasiodonin Lasiokaurin |
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