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Relapsing polychondritis with severe aortic insufficiency
Authors:Dr. R. Manna  V. Annese  G. Ghirlanda  F. Pennestri'  A. V. Greco  M. A. Pala  G. B. Bochicchio  M. Magaro'
Affiliation:(1) Clinical Medicine Institute, Catholic University of Sacred Heart, Rome, Italy;(2) Department of Cardiology, Catholic University of Sacred Heart, Rome, Italy;(3) Department of Rheumatology, Catholic University of Sacred Heart, Rome, Italy;(4) Istituto di Clinica Medica, Università Cattolica del Sacro Cuore, Roma Policlinico A. Gemelli, Largo Gemelli 8, 00168 Roma, Italia
Abstract:Summary Relapsing polychondritis (RP) is a rare disease characterized by auricular, nasal and respiratory tract chondritis, ocular inflammation, inflammatory polyarthritis and cardiovascular abnormalities. Here we describe a patient with a five-year history of mild nasal and auricular chondritis, which suddenly developed into a severe aortic insufficiency with rest dyspnea. The pathogenesis and the management of this rare connective tissue disease are discussed.
Keywords:Relapsing Polychondritis  Aortic Insufficiency
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