Meige综合征临床误诊九例分析

目的 探讨Meige综合征的临床特点、诊断、误诊原因及治疗. 方法 对广州市第一人民医院脑系外科收治的9例误诊的Meige综合征患者的临床特点、误诊原因及治疗进行回顾性分析.结果 Meige综合征典型表现为阵发性双侧眼睑痉挛,伴或不伴有双侧口颌部及其他部位肌肉不随意、对称性、不规则阵发性收缩,临床上易被误诊为重症肌无力、面肌痉挛、神经官能症和迟发性运动障碍等,误诊的原因主要是对本病认识不足.本组9例患者经治疗后症状均有明显改善.结论 虽然Meige综合征临床特点较明显,但发病早期易误诊,要注意和其他疾病鉴别.

Clinical misdiagnosis of Meige syndrome: report of 9 cases

Objective To investigate the clinical characteristics, diagnosis, misdiagnosis and treatment of Meige syndrome. Methods The clinical characteristics,misdiagnosis and treatment of 9 patients with Meige syndrome were reviewed retrospectively. Results The typical characteristics of Meige syndrome were bilateral paroxysmal blepharospasm with or without bilateral oromandibular and other parts' abnormal movements that were paroxysmal and symmetrical. Patients with Meige syndrome were usually misdiagnosed as having myasthenia gravis, hemifacial spasm, neurosis or tardive dyskinesia. Not having enough knowledge about Meige syndrome was the main reason for misdiagnosis. And all the patients got improvements after the treatment. Conclusion The clinical features of Meige syndrome are typical, but misdiagnosis can often be made in the early stage of Meige syndrome, thus,special attention should be paid on the differential diagnosis of Meige syndrome.