| 血CGRP、ET-1和NSE在新生儿HIE的变化及其临床意义 |
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| 引用本文： | 王绪玲,廖培元,张恩胜.血CGRP、ET-1和NSE在新生儿HIE的变化及其临床意义[J].标记免疫分析与临床,2011,18(1):28-32. |
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| 作者姓名： | 王绪玲 廖培元 张恩胜 |
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| 作者单位： | 滕州市中心人民医院; |
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| 摘 要： | 检测不同时期、不同严重程度的新生儿缺氧缺血性脑病(HIE)患儿血神经元特异性烯醇化酶(NSE)、内皮素-1(ET-1)和降钙素基因相关肽(CGRP)的含量,探讨NSE、ET-1和CGRP在新生儿HIE中的变化及其临床意义. 分别于出生即刻、3天、7天采集对照组、新生儿HIE轻度组、中度组、重度组的血标本,采用放射免疫法...
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| 关 键 词： | 新生儿 缺血缺氧性脑病 神经元特异性烯醇化酶 内皮素 降钙素基因相关肽 |
The Change and Clinical Significance of Blood CGRP, ET-1 and NSE in Neonatal Hypoxic-Ischemic Encephalopathy |
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| WANG Xu-ling,LIAO Pei-yuan,ZHANG En-sheng.The Change and Clinical Significance of Blood CGRP, ET-1 and NSE in Neonatal Hypoxic-Ischemic Encephalopathy[J].Labeled Immunoassays and Clinical Medicine,2011,18(1):28-32. |
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| Authors: | WANG Xu-ling LIAO Pei-yuan ZHANG En-sheng |
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| Institution: | WANG Xu-ling,LIAO Pei-yuan,ZHANG En-sheng(Department of Central Laboratory,The People's Central Hospital of Tengzhou,Tengzhou 277500,China) |
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| Abstract: | To detect the blood levels of endothelin(ET-1),neuron-specific enolase(NSE) and calcitonin gene-related peptide(CGRP) of neonates with different grades of hypoxic-ischemic encephalopathy(HIE),and to explore the clinical significance of serum ET-1,NSE and CGRP in the progress of HIE.The blood concentrations of ET-1,NSE and CGRP in 46 neonates with HIE and 15 control neonates at different birth time were detected by radioimmunoassay.The results showed that the blood levels of ET-1,NSE in neonates with HIE at ... |
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| Keywords: | Neonate Hypoxic-ischemic encephalopathy Neuron-specific enolase Endothelin Calcitonin gene-related peptide |
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