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肥胖并发糖尿病患者心脏结构与功能的变化
引用本文:鲁豫,鲁平,袁建军,文世林. 肥胖并发糖尿病患者心脏结构与功能的变化[J]. 郑州大学学报(医学版), 2003, 38(5): 724-726
作者姓名:鲁豫  鲁平  袁建军  文世林
作者单位:河南省人民医院超声诊断科,郑州,450003;河南省人民医院内分泌科,郑州,450003
基金项目:河南省科技攻关基金资助项目 0124170642
摘    要:目的应用彩色多普勒超声探讨肥胖并发2型糖尿病患者心脏结构功能及变化特点.方法单纯肥胖组40例,单纯2型糖尿病组49例,肥胖并发2型糖尿病组64例,对3组患者的彩色多普勒超声检查结果及相关临床资料进行对比分析.结果肥胖并发2型糖尿病组的心脏左房内径、舒张末期左心室内径、左心室后壁厚度、室间隔厚度、左心室质量指数均大于单纯2型糖尿病组及单纯肥胖组(P<0.05),其射血分数与左心室质量指数和体重指数呈负相关(r=-0.714、-0.397).收缩及舒张功能异常率,3组间比较差异有统计学意义(P<0.05).结论肥胖并发糖尿病能明显加重患者左心室结构和功能损害.

关 键 词:肥胖  2型糖尿病  心功能  彩色多普勒超声心动图
修稿时间:2003-03-10

Clinical feature of cardiac structure and function in patients with obese diabetes mellitus
LU Yu ),LU Ping ),YUAN Jianjun ),WEN Shilin ) ). Clinical feature of cardiac structure and function in patients with obese diabetes mellitus[J]. Journal of Zhengzhou University: Med Sci, 2003, 38(5): 724-726
Authors:LU Yu )  LU Ping )  YUAN Jianjun )  WEN Shilin ) )
Affiliation:LU Yu 1),LU Ping 2),YUAN Jianjun 1),WEN Shilin 2) 1)Department of Ultrasound,Henan Provincial People's Hospital,Zhengzhou 450003 2)Department of Endocrinology,Henan Provincial People's Hospital,Zhengzhou 450003
Abstract:Aim:To investigate the feature of cardiac structure and function in cases of obese type 2 diabetes mellitus(T2DM). Methods:A total of 152 cases were allocated into 3 groups: simple obese group ( n =40), simple T2DM group ( n=49 ), and obese T2DM group ( n =64).Color Doppler Echocardiogram was performed to all the cases. Results:LA,LVd,LVPWd,IVSd, and LVMI in obese T2DM group were the highest among 3 groups ( P <0.05). Multiple liner regression showed that LVEF was negatively correlated to LVMI and BMI in obese T2DM group( r =-0.714,-0.397, P < 0.05 ). In terms of cardiac systolic rate and diastolic dysfunction rate, it was significantly different among 3 groups ( P < 0.05 ).Conclusion:Obese combined with T2DM potentiates the injuries of cardiac structure and function.
Keywords:obesity  type 2 diabetes  heart function  Color Doppler Echocardiography
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