慢性前列腺炎中医证型与血清前列腺特异性抗原的相关性

目的：通过检测慢性前列腺炎患者的血清前列腺特异性抗原（PSA）值,探讨慢性前列腺炎证型与血清PSA的关系.方法：选取门诊符合NIH慢性前列腺炎诊断标准患者149例,严格按中医辨证分为湿热下注,脾肾气虚,气滞血瘀,肾阴亏虚四组;用化学发光微粒子免疫法检测各组血清PSA水平.结果：湿热下注与气滞血瘀两组PSA水平有显著性差异（P＜0.01）,脾肾气虚,肾阴亏虚二个证型与PSA水平无显著性差异（（P＞0.05）.结论：湿热下注证与气滞血瘀证对PSA变化影响较大,湿热下注证与气滞血瘀证均与PSA水平呈正相关,而脾肾气虚证、肾阴亏虚证与PSA水平相关性不大.

Relevance of chronic prostatitis TCM syndrome and serum PSA

Objectives： Through detecting serum prostate specific antigen （PSA） value of patients with chronic prostatitis, to explore the relationship between chronic prostatitis syndrome and serum PSA. Methods： 149 out -patient patients in line with NIH chronic prostatitis diagnostic criteria were selected and divided into the damp - heat, spleen - and - kidney deficiency, Qi stagnation and yin deficiency four groups strictly following the TCM differentiation. Chemiluminescent microparticle immunoassay was adopted for the detection of serum PSA levels. Result： The PSA level of Damp - heat group and Qi stagnation group was significantly different （ P 〈0.01 ）, while difference in the TCM syndrome and PSA level of spleen - and - kidney deficiency group and yin defieieney group was not significant （P 〉 0.05）. Conclusion： Damp- heat and Qi stagnation have great effects on changes in PSA and are positively correlated with PSA levels, while the spleen - and - kidney deficiency and yin deficiency is of lit- fie relevance to PSA levels.