LEEP刀锥切术对宫颈癌患者生育能力和妊娠结局的影响

目的：探究宫颈LEEP刀锥切术对宫颈CINI-III患者生育能力和妊娠结局的影响。方法：选择我院妇科2009年2月至2011年2月收治的50例早期宫颈癌患者和同期孕前门诊就诊的50例无宫颈锥切术史的计划妊娠妇女为研究对象。比较两组女性生育能力和母婴结局。结果：实验组50例患者有49例（96％）妊娠，对照组50例患者有42例（84％），差异有显著性（P＜0.05）；实验组50例患者有8例（16％）不孕，对照组50例患者有1例（2％）不孕，差异有显著性（P＜0.05）；实验组患者剖宫产率明显高于对照组，差异有显著性（P＜0.05）；实验组胎膜早破、早产、新生儿窒息和新生儿低体重均明显高于对照组患者的，差异有显著性（P＜0.05）。结论：宫颈LEEP刀锥切术后宫颈CINI-III妊娠率较正常人群稍差，而且也在一定程度上增加胎膜早破、胎儿早产、新生儿窒息和新生儿低体重的发生率。

Impact on the fertility and pregnancy of patients with cervical cancer of LEEP knife conization

To investigate the impact on the fertility and pregnancy of patients with cervical cancer by cervical LEEP knife conization.Methods：50 patients with early cervical cancer and 50 outpatients with-out cervical conization history and planned for pregnancy in our hospital from February 2009 to February 201 1 were chosen as the study objects.Female fertility and pregnancy outcome of the 2 groups were compared.Results：There were 49 pregnancy women （pregnancy rate of 96%）in the experimental group and 42 pregnancy women （pregnancy rate of 84%）in the control group,with significant difference （P〈0.05 ）.There were 8 cases of infertility in the experimental group （infertility rate of 16%）and 1 case of infertility in the control group （infertility rate of 2%）, with significant difference （P〈0.05 ）.The rate of cesarean section in the experimental group was significantly higher than that in control group,which was of significant difference （P〈0.05）.Premature rupture of fetal mem-branes,premature delivery,neonatal asphyxia and neonatal low birth weight of experimental group were significantly higher than those in control group,which was significant difference （P〈0.05 ）.Conclusion：Cervical CINI-III pregnancy rate after cervical LEEP knife conization is lower than the normal population,but it also increases the in-cidence of premature rupture of fetal membranes,premature birth,neonatal asphyxia and low birth weight.