来曲唑与氯米芬应用于多囊卵巢综合征不孕患者临床疗效分析研究 |
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引用本文: | 吕雪梅,王苏梅,董云玲,刘锦云,樊云井,江平,丁海青,魏斌.来曲唑与氯米芬应用于多囊卵巢综合征不孕患者临床疗效分析研究[J].中国性科学,2014(3):80-82. |
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作者姓名: | 吕雪梅 王苏梅 董云玲 刘锦云 樊云井 江平 丁海青 魏斌 |
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作者单位: | 山东省计划生育科学技术研究所,山东省优生技术重点实验室,济南250002 |
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摘 要: | 目的:比较来曲唑与氯米芬应用于多囊卵巢综合征不孕患者临床疗效分析。方法:选择2010年1月至2012年10月就诊于我院不孕门诊的PCOS不孕患者70例,随机分为两组,氯米芬组34例和来曲唑组36例,70例患者共进行129个促排卵周期,分析两组的临床治疗效果。结果:来曲唑组临床妊娠率为38.89%,明显优于氯米芬组17.65%的妊娠率,二者比较差异有统计学意义(P<0.05)。来曲唑组在优势卵泡率、排卵率及临床妊娠率方面均优于氯米芬组,二者比较差异有统计学意义(P<0.05)。结论:来曲唑应用于多囊卵巢综合征不孕患者,可以明显提高患者的临床妊娠率,值得在一定范围内临床推广应用。
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关 键 词: | 多囊卵巢综合征 不孕 促排卵 来曲唑 氯米芬 临床妊娠率 |
Comparation between letrozole and clomiphene crowe in their clinical effects on patients with polycystic ovary syndrome |
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Institution: | LV Xuemei,WANG Sumei,DONG Yunling,LIU Jinyun,FAN Yunjing,JIANG Ping,DING Haiqing( 1.Shandong Research Institute of Family Planning Science and Technology, Shandong Province Key Laboratory of Eugenic Technology, Jinan 250002, China;) |
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Abstract: | Objectives: To compare the clinical effect of ovulation induction of letrozole and clomiphene crowe on patients with polycystic ovary syndrome (PCOS).Methods: 70 patients with PCOS hospitalized from January 2010 to October 2012 were divided into 2 groups randomly: 34 cases in clomiphene crowe group and 38 cases in letrozole group.70 patients were given 129 cycles of ovulation induction.The effect of ovulation induction of the 2 groups were compared and analyzed.Results: The clinical pregnancy rate in letrozole group was 38.89%,which was significantly higher than that in clomiphene crowe group (17.65%) (P <0.05) ; There was significant differences between the two groups in the dominant follicle,ovulation rate and clinical pregnancy (P < 0.05).Conclusion: Letrozole is effective and conducive to the development of endometrium for patients with PCOS. |
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Keywords: | Polycystic ovary syndrome Infertility ovulation induction Letrozole Clomiphene crowe Clinical pregnancy rate |
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