| 利培酮抑制3T3-L1前脂肪细胞的分化 |
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| 引用本文： | 张高丽,张弋,于海川,张新雅.利培酮抑制3T3-L1前脂肪细胞的分化[J].国际检验医学杂志,2016(15):2108-2109. |
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| 作者姓名： | 张高丽 张弋 于海川 张新雅 |
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| 作者单位： | 1. 河南省周口市中心血站 466000;2. 四川成都军区总医院,成都,610083;3. 新乡医学院医学检验学院,河南新乡,453003 |
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| 摘 要： | 目的研究利培酮对3T3-L1前脂肪细胞分化的影响。方法采用经典的激素鸡尾酒法诱导3T3-L1前脂肪细胞分化为成熟的脂肪细胞,油红O染色观察。向诱导培养基中加入利培酮研究其对3T3-L1前脂肪细胞分化的影响。结果用激素鸡尾酒法成功地将3T3-L1前脂肪细胞诱导为成熟的脂肪细胞。0.1、1、10μmol/L的利培酮均能够抑制3T3-L1前脂肪细胞的分化。结论利培酮能够抑制3T3-L1前脂肪细胞的分化。
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| 关 键 词： | 利培酮 3T3-L1细胞 分化 |
Risperidone inhibits 3T3-L1 pre-adipocytes differentiation |
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| Abstract: | Objective To investigate the influence of risperidone on differentiation of 3T3‐L1 pre‐adipocytes .Methods 3T3‐L1 pre‐adipocytes were induced to differentiate into mature adipocytes by adopting the classic hormone cocktail method and observed by the oil red O staining .Meanwhile ,the inducing medium was added with risperidone for studying its influence on 3T3‐L1 pre‐adi‐pocytes differentiation .Results 3T3‐L1 pre‐adipocytes were successfully differentiated into the mature adipocytes ,0 .1 ,1 ,10μmol/L risperidone all could inhibit the differentiation of 3T3‐L1 pre‐adipocytes .Conclusion Risperidone can inhibit the differentiation of 3T3‐L1 pre‐adipocytes . |
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| Keywords: | risperidone 3T3-L1 cell differentiation |
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