动脉自旋标记灌注成像在癫痫的研究进展

癫痫是脑神经元异常放电引起反复痫性发作的脑功能失调综合征。对癫痫病人脑功能的研究成为近年来的研究热点。其中动脉自旋标记(ASL)灌注成像是一种无创定量测量脑血流灌注量的MR功能成像新技术，可以反映癫痫病人脑血流动力学的相关情况，能为更好地揭示癫痫的病理生理机制提供新的理论依据。就ASL新技术在癫痫的研究进展及临床应用进行综述。

Progress of arterial spin labeling perfusion in epilepsy

Epilepsy is a brain dysfunction syndrome, which is caused by abnormal discharge of cerebral neurons. It has become a hot topic in the study of brain function in patients with epilepsy at present. Arterial spin labeling (ASL) perfusion is one of the advanced magnetic resonance imaging (MRI) technologies that can measure the cerebral blood flow quantitatively and noninvasively. It is able to reveal the cerebral hemodynamics in epilepsy patients and to provide a new theoretical basis for the pathophysiological mechanism of epilepsy. Recent advances in this field and its applications in clinic were reviewed in this article.