| 大气细颗粒物（PM 2.5）对呼吸系统的损伤作用机制概述 |
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| 引用本文： | 鞠娅,沈若冰,余小萍.大气细颗粒物（PM 2.5）对呼吸系统的损伤作用机制概述[J].国际呼吸杂志,2016(21):1677-1680. |
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| 作者姓名： | 鞠娅 沈若冰 余小萍 |
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| 作者单位： | 传统中医科, 上海中医药大学曙光临床医学院,200021 |
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| 基金项目： | 上海市卫生局面上项目(201314113)@@@@Project of Shanghai Health Bureau(201314113) |
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| 摘 要： | 大气细颗粒物(PM 2.5)是空气污染的主要成分，可以进入呼吸道深部，导致各种呼吸系统疾病，据研究可能与其能引起机体氧化应激、炎症反应、免疫功能失调、DNA 损伤、钙稳态失衡、神经源性炎症有关。本文就 PM 2.5对呼吸系统的损伤作用机制作一综述。
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| 关 键 词： | PM 2.5 呼吸系统 氧化应激 炎症损伤 |
An overview of fine particulate matter(PM 2.5)on the mechanism of the injury of respiratory system |
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| Abstract: | Fine particulate matter (PM 2.5) is the main component of air pollution,which can enter deeply into respiratory department,leading to a variety of respiratory disease.According to the researches,it may be caused by body oxidative stress,inflammatory reaction,immune dysfunction,DNA damage,calcium homeostasis imbalance,neurogenic inflammation.The article is circled on the mechanism of PM 2.5 on respiratory injury. |
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| Keywords: | PM 2 5 Respiratory system Oxidative stress Inflammatory injury |
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