首页 | 本学科首页   官方微博 | 高级检索  
     

藏药五脉绿绒蒿中非生物碱成分
引用本文:尚小雅,李冲,张承忠,杨永春,石建功. 藏药五脉绿绒蒿中非生物碱成分[J]. 中国中药杂志, 2006, 31(6): 468-471
作者姓名:尚小雅  李冲  张承忠  杨永春  石建功
作者单位:1. 中国医学科学院,中国协和医科大学,药物研究所,北京,100050
2. 兰州大学,药学院,甘肃,兰州,730000
基金项目:北京市科委248生物技术项目
摘    要:目的:研究藏药五脉绿绒蒿Meconopsis quintuplinervia的化学成分。方法:应用色谱技术分离纯化,用波谱学方法确定化合物结构。结果:从乙醇提取物中分离得到12个化合物,分别鉴定为:槲皮素-3-O-β-D-葡萄糖苷(Ⅰ),槲皮素-3-O-[β-D-半乳糖(1→6)]-β-D-葡萄糖苷(Ⅱ),山柰素-3-O-[β-D-葡萄糖(1→2)]-β-D-葡萄糖苷(Ⅲ),异鼠李黄素-3-O-[β-D-半乳糖苷(1→6)]-β-D-葡萄糖(Ⅳ),咖啡酸(Ⅴ),原儿茶酸(Ⅵ),对羟基肉桂酸(Ⅶ),2-(3,4-二羟苯基)-乙醇β-D-吡喃葡萄糖苷(Ⅷ),对羟基苯甲酸β-D-吡喃葡萄糖酯苷(Ⅸ),肉桂酸4-O-β-D-吡喃葡萄糖苷(Ⅹ),5,7-二羟基色原酮(Ⅺ),胡萝卜苷(Ⅻ)。结论:除Ⅵ和Ⅻ外,其余10个化合物均为首次从该属植物中发现。

关 键 词:藏药  罂粟科  五脉绿绒蒿  黄酮苷  芳香酸  芳香吡喃葡萄糖苷
文章编号:1001-5302(2006)06-0468-04
收稿时间:2005-09-25
修稿时间:2005-09-25

Non-alkaloid constituents from a Tibetan medicine Meconopsis quintuplinervia
SHANG Xiao-ya ;LI Chong ;ZHANG Cheng-zhong ;YANG Yongchun ;SHI Jian-gong. Non-alkaloid constituents from a Tibetan medicine Meconopsis quintuplinervia[J]. China Journal of Chinese Materia Medica, 2006, 31(6): 468-471
Authors:SHANG Xiao-ya   LI Chong   ZHANG Cheng-zhong   YANG Yongchun   SHI Jian-gong
Affiliation:1 Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, 2. School of Pharmaceutical Sciences, Lanzhou University,Lanzhou 730000, China
Abstract:OBJECTIVE: To study the chemical constituents of a Tibetan medicine Meconopsis quintuplinervia. METHOD: Column chromatographic techniques were applied to isolate constituents. A combination of IR, MS and NMR spectroscopy was used to identify structures of constituents. RESULT: Twelve compounds were isolated from the ethanolic extract and their structures were elucidated as quercetin 3-O-beta-D-glucopyranoside (I), quercetin 3-O-beta-D-galactopyranosyl-(1-->6)-glucopyranoside (II), kaempferol 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (III), isorhamnetin 3-0-beta-D-galactopyranosyl-(1-->6)-beta-D-glucopyranoside (IV), caffeic acid (V), protocatechuic acid (VI), p-hydroxycinnamic (VII), 2-(3,4-dihydroxyphenyl )-ethyl-O-beta-D-glucopyranoside (VIII), p-hydroxybenzoyl-beta-D-glucopyranoside (IX), 4-O-beta-D-glucopyranosyl-(Z)-p-coumaric acid (X), 5, 7-dihydroxy-4H-4-chromenone (XI), daucosterol (XII). CONCLUSION: Ten compounds were isolated from this genus for the first time except for XI and XII.
Keywords:Tibetan medicine  Papaveraceae  Meconopsis quintuplinervia  flavonol glycosides  aromatic acid  aromatic glucopyranoside
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号