神经干细胞移植及术后处理:附70例报告

目的总结脑损伤和脊髓损伤后神经功能障碍病人的神经干细胞移植及术后相关问题的处理经验。方法对70例脑和脊髓神经干细胞移植病人术后相关问题的处理和恢复情况进行回顾分析。结果除3例病人出现颅内感染,通过腰穿椎管内给抗生素最终出院外,其余病人术后均顺利出院,而手术后有3例病人性功能完全恢复,5例病人大小便可以自己控制。结论对于脑损伤功能障碍或者脊髓损伤的截瘫病人,进行脑内或者脊髓神经干细胞移植,对于促进脑功能或者脊髓功能恢复有意义,术后相关问题的处理是手术预后的重要保障。

Neural stem cell transplantation and postoperative management:report of 70 cases

Objective To review the operations of neural stem cells transplantation in patients with brain trauma or spinal cord injury and their postoperative management. Methods A retrospective analysis was conducted in 70 cases of brain trauma or paraplegia treated with neural stem cell transplantation in the recent two years. Results All patients were smoothly discharged except for 3 who developed intracraninal infection corrected with antibiotics via the vertebral canal. Another 3 patients with total loss of sexual function after spinal cord injury for over 1 year recovered sexual function after neural stem cell transplan- tation. Conclusion Neural stem cell transplantation can promote the functional recovery of the brain and spinal cord in patients with brain trauma or spinal cord injury. Proper postoperative management for the patients is crucial to ensure favorable prognosis.