基于模型的耳蜗核反应特性研究

目的耳蜗核内的信息处理,是中枢对听觉信息处理的最先一环。根据神经元对短纯音刺激反应的时间特性来分类,耳蜗核神经元可以分为多种反应类型。我们用模型的方法来探讨这些不同反应类型的机制。方法基于Matlab7.0平台,在经典的积分-放电模型基础上构建时间编码模型。结果模型通过改变与神经元特性有关的参数可以很好的模拟耳蜗核中初级反应型、梳状型、给声开始型和建立型神经元。结论耳蜗核神经元反应特性主要是由神经元本身的特性决定。模型仿真结果与文献十分吻合,为后续研究听觉系统的作用机制打下基础。

Response properties of cochlear nucleus neurons: a digital model-based study

Objective To investigate the mechanisms of different response patterns of the cochlear nucleus neurons based on a digital model.Methods Based on the platform of Matlab7.0 and the integrate-and-fire model,we constructed the temporal coding model.Results The model well simulated the response types of the primary-like,chopper,onset and buildup neurons by changing the settings of some parameters related to the properties of the neurons.Conclusions The properties of the neurons dictate the response patterns of t...