| Abstract: | Temporary ischemia of the gall bladder was produced in rabbits by application of a silk ligature to the cystic artery. Histological examination revealed vascular disturbances, consisting of hyperemia, stasis of blood, and focal hemorrhages. Electron-microscopic investigation showed an increase in the number of dark epithelial cells, widening of the intercellular space, and loosening of the structure of the basement membrane with the formation of defects in it and invagination of epithelial cells into the submucosa. The most marked changes were found after occlusion of the cystic artery for 30 min on three occasions. The severity of the destructive changes depend not so much on the duration of ischemia as on the number of occlusions.Department of Pathological Anatomy, Stomatological Faculty, Medical Stomatological Institute, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR, A. I. Strukov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 4, pp. 489–492, April, 1976. |
