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吉非替尼治疗晚期非小细胞肺癌疗效分析
引用本文:张进川,李洪霞,张东,安莉. 吉非替尼治疗晚期非小细胞肺癌疗效分析[J]. 中国临床保健杂志, 2007, 10(6): 563-565
作者姓名:张进川  李洪霞  张东  安莉
作者单位:解放军总医院南楼呼吸科,北京,100853;解放军总医院南楼呼吸科,北京,100853;解放军总医院南楼呼吸科,北京,100853;解放军总医院南楼呼吸科,北京,100853
摘    要:目的观察吉非替尼对晚期非小细胞肺癌患者的疗效。方法对吉非替尼治疗的非小细胞肺癌22例进行分析。结果22例中可评估的14例中(5例疾病稳定,2例完全缓解,1例部分缓解)有效率21.4%,临床获益率8/14(57.2%)。结论吉非替尼对晚期非小细胞肺癌疗效较好,其副反应相对小,耐受性好。

关 键 词:  非小细胞肺  肿瘤治疗方案
文章编号:1672-6790(2007)06-0563-03
修稿时间:2007-05-15

The efficacy of gefitinib in treating non-small cell lung cancer
ZHANG Jinchuan,LI Hongxia,ZHANG Dong,AN Li. The efficacy of gefitinib in treating non-small cell lung cancer[J]. Chinese Journal of Clinical Healthcare, 2007, 10(6): 563-565
Authors:ZHANG Jinchuan  LI Hongxia  ZHANG Dong  AN Li
Affiliation:Department of Respiratory Medicine of Geriatrics, General Hospital of PLA ,Beijing 100853, China
Abstract:Objective To study the efficacy of Gefitinib(Iressa) in treating elderly patients with advanced non-small cell lung cancer.Methods 22 elderly patients with advanced non-small cell lung cancer treated by Gfitinib from Apr 2004 to Dem 2006 with Gfitinib were analyzed.Results Among 14 patients appreciable from all 22 patients,complete response(CR) in 2 cases,partial response(PR) in 1case,stable disease(SD) in 5 cases,so the clinical benefit response(2 1 5)rate was 57.2% and the tumor response(2 1) rate was 21.4%.Conclusion Gefitinib is an effective orally drug in the treatment of patients with non-small cell lung cancer.The of toxicity with Gefitinib is lower and can be well acceptable.
Keywords:Carcinima  non-small-cell lung  Antineoplastic protocols
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