| 索拉非尼治疗肝细胞癌患者的不良反应及其对预后的影响 |
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| 引用本文： | 安林静,郝丽燕,张昕,张丽娜,李因茵,陆荫英,王春平,曲建慧,杨永平. 索拉非尼治疗肝细胞癌患者的不良反应及其对预后的影响[J]. 解放军护理杂志, 2011, 28(17): 8-11 |
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| 作者姓名： | 安林静 郝丽燕 张昕 张丽娜 李因茵 陆荫英 王春平 曲建慧 杨永平 |
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| 作者单位： | 解放军第302医院,肝脏肿瘤诊疗与研究中心,北京,100039 |
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| 基金项目： | 国家重大专项基金资助项目 |
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| 摘 要： | 目的 了解索拉非尼治疗进展期肝细胞癌(hepatocellular carcinoma,HCC)患者相关不良反应的发生率及其对预后的影响.方法 依据美国国立癌症研究所毒性判定标准观察索拉非尼治疗110例进展期HCC患者相关不良反应;Kaplan-Meier曲线分析相关不良反应对进展期HCC预后的影响.结果 索拉非尼相关...
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| 关 键 词： | 索拉非尼 进展期肝细胞癌 临床护理 生存期 |
Sorafenib Treatment-related Adverse Events on Prognosis in Patients with Hepatocellular Carcinomas |
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| AN Lin-jing,HAO Li-yan,ZHANG Xin,ZHANG Li-na,LI Yin-yin,LU Yin-ying,WANG Chun-ping,QU Jian-hui,YANG Yong-ping. Sorafenib Treatment-related Adverse Events on Prognosis in Patients with Hepatocellular Carcinomas[J]. Nursing Journal of Chinese People's Liberation Army, 2011, 28(17): 8-11 |
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| Authors: | AN Lin-jing HAO Li-yan ZHANG Xin ZHANG Li-na LI Yin-yin LU Yin-ying WANG Chun-ping QU Jian-hui YANG Yong-ping |
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| Affiliation: | AN Lin-jing,HAO Li-yan,ZHANG Xin,ZHANG Li-na,LI Yin-yin,LU Yin-ying,WANG Chun-ping,QU Jian-hui,YANG Yong-ping(Therapeutic Research Center for Hepatocellular Carcinoma,No.302 Hospital of PLA,Beijing 100039,China) |
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| Abstract: | Objective To investigate the incidence of Sorafenib treatment-related adverse events in the patients with advanced hepatocellular carcinoma(HCC) and its influence on the prognosis.Methods The baseline characteristics and outcomes of 110 patients with advanced HCC treated by sorafenib were collected.The treatment-related adverse events were determined according to the National Cancer Institute Common Toxicity Criteria.Kaplan-Meier method were used to determine the influence of the adverse events on the progn... |
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| Keywords: | Sorafenib advanced hepatocellular carcinoma clinical nursing overall survival(OS) |
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