放大内镜对幽门螺杆菌感染性胃炎诊断的实用性

目的通过放大内镜观察胃黏膜微细形态的改变来判断Hp感染，以探讨放大内镜诊断幽门螺杆菌感染性胃炎的临床应用价值。方法采用日本Olympus GIFQ-240电子放大内镜，选取200例程度不同的消化不良患者行变焦放大观察病变部位胃黏膜的微细结构。结果放大内镜诊断Hp感染与病理组织学及快速尿素酶检测无统计学差异；将放大内镜下集合静脉观察大体分三型，R型与I型或D型比较有显著性差异（P〈0．01），后两型存在Hp感染；胃小凹分为五型，A型胃小凹为正常胃黏膜，x^2检验证实，C型小凹对应黏膜的Hp感染率高于B型（P〈0．01），其余各型间Hp感染率无统计学差异（P〉0．05），B、C、D、E存在Hp感染。结论电子放大内镜对诊断幽门螺杆菌感染性胃炎有临床应用价值。

Practicability of Magnifying Endoscopy in Diagnosis of Helicobacter Pylori Associated Gastritis

Objective This study through magnifying endoscopy to view gastrer mucosa appearance to judgement Helicobacter pylori infestation. To evaluate the efficacy of magnifying endoscopy in diagnosis of Helicobacter .pylori associativity gastritis. Methods The fine structure of gastficmucosa in 200 patients with different types of chronic gastritis was studied using Olympus GIF 2. Q240Z magnifying endoscopy. The fine structure of gastric mucosa were compared with the results of rapid urease test. Using chi - squared test to catty out statistics analysis on the basis of result. Results Collecting venules in the anterior wall at lower part of gastric corpus were subgrouped into types Regular, Irregular and Disappeared. Among them, Hp infection rate in type Regularwas significantly lower than that in the other two types（ P 〈 0.01） .The gastric mucosa with type C pits had a higher infection rate than that with type B pits （P 〈 0.01 ）. The rest type have no statistic difference （P 〉 0.05）. Conclusion Our results indicated that magnifying endoscopy might be potentially valuable in the diagnosis of Hp infection of gastric mucosa.