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重视脂蛋白胆固醇的检测
引用本文:有军 任丽敏 等. 重视脂蛋白胆固醇的检测[J]. 上海医学检验杂志, 2001, 16(6): 358-360
作者姓名:有军 任丽敏 等
作者单位:上海市浦东新区公利医院 上海200135(有军,任丽敏),上海市浦东新区公利医院 上海200135(周强)
摘    要:目的 了解病人血清中高,低密度脂蛋白胆固醇(HDL-C,LDL-C)和载脂蛋白A、B(Aop-A、B)的关系。方法 将市场上的某公司载脂蛋白检测试剂和具国际标准化的试剂,对病人血清作对比测定,了解差距;同时对血清作HDL-C、LDL-C,总胆固醇(TC),三酰甘油(TG)测定。结果 实验用国产载脂蛋白试剂和标准化试剂的检测结果对比差距很大,HDL-C、LDL-C含量和相应AopA1,AopB间无明确的数量关系。结论 对高血脂和糖尿病病人作心脏损害的危险程度的了解时,应重视作HDL-C、LDL-C的检测。

关 键 词:脂蛋白 高脂血症 脂蛋白胆固醇 检测

The significance of the determination of lipoprotein cholesterols
YOU Jun,REN Limin,ZHOU Qiang,Gongli Hospital,Shanghai ,China. The significance of the determination of lipoprotein cholesterols[J]. Shanghai Journal of Medical Laboratory Sciences, 2001, 16(6): 358-360
Authors:YOU Jun  REN Limin  ZHOU Qiang  Gongli Hospital  Shanghai   China
Affiliation:YOU Jun,REN Limin,ZHOU Qiang,Gongli Hospital,Shanghai 200135,China
Abstract:Objective To study the relationship between HDL cholesterol, LDL cholesterol and Aop A, Aop B in patient serum. Method To determine the patient serum Apo A, B with an internationally standardized reagent kit and a common used kit. and to determine the HDL cholesterol, LDL cholesterol, total cholesterol, and triglyceride at the same time, Results The quality of the reagent seriously affected the test results. Obviously there was not quantitative relation between HDL cholesterol and Apo A; or LDL cholesterol and Apo B. Conclusion Should pay great attention to the determination of HDL cholesterol and LDL cholesterol for the patients with hyperlipidemia and /or diabetes to detect the early heart damage.
Keywords:Hyperlipidemia  Apolipoprotein  Lipoprotein cholesterol
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