椎-基底动脉延长扩张症患者颅内动脉影像学测量对照研究

目的分析和探讨椎-基底动脉延长扩张症（VBD）患者颅内动脉扩张程度，并观察脑干受压情况。方法回顾性分析26例经临床确诊VBD患者和30例正常对照组磁共振血管造影（MRA）及CT血管造影（cTA）图像，观察脑干受压情况，并利用MRA图像对基底动脉、颈内动脉、大脑中动脉直径测量分析。结果26例VBD患者中，8例可见脑干不同程度受压，其中桥脑受压5例，延髓受压3例，但临床均未发现相应症状及体征。利用MRA图像对VBD组和正常对照组颅内大动脉进行测量，两组间基底动脉、颈内动脉（颅内段）比较差异具有统计学意义（P〈0．05），两组间大脑中动脉差异无统计学意义（P〉0．05）。结论部分VBD患者，脑干可见明显受压，但临床症状不明显。VBD患者椎-基底动脉扩张以外，颅内其他动脉也同时存在不同程度扩张，临床应给予高度重视。

Comparative study on imaging measurement of intracranial arteries in patients with vertebrobasilar dolichoectasia

Objective To analyze and discuss the expansion of intracranial artery for vertebrobasilar dolichoectasia（VBD） patients,and observe the compression of the brain stem. Methods By retrospective analysis of magnetic resonance angiography（MRA） and computed tomography angiography（CTA） images for clinical diagnosis of 26 cases of VBD patients and 30 normal controls, the compression of brain stem condition was observed, and using MRA image,the diameters of the basilar artery,internal carotid artery and middle cerebral artery were measured and analyzed. Results In 9,6 VBD cases, 8 cases showed different degrees of brain stem compression, the compression including the pons 5 cases,medulla oblongata compression 3 cases, but the corresponding clinical symptoms and signs were not found. By measuring the intracranial arteries of VBD group and normal control group using MRA, for the basilar artery and internal carotid artery （intracranial segment）, the difference were statistically significant （P 0.05） ,but the middle cerebral artery showed no statistical significance （P ~ 0.05）. Conclusion For some VBD patients, the brain stem was compressed obviously, but no obvious clinical symptoms appeared. For VBD patients,in addition to vertebrobasilar dilatation, other intracranial arteries also exist at different degrees of expansion, and the clinical attention should be given.