Fibrillary glomerulonephritis in a patient with type 2 diabetes mellitus |
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Authors: | Gielen G A L Wetzels J F M Steenbergen E J Mudde A H |
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Affiliation: | Department of Internal Medicine, Slingeland Hospital, Doetinchem, The Netherlands. |
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Abstract: | We report a 62-year-old man with documented type 2 diabetes mellitus and hypertension, who presented with a rapid deterioration in renal function. The sudden decrease in renal function in this well-controlled diabetic patient prompted us to consider a nondiabetic and nonhypertensive cause. The urinary sediment showed a glomerular haematuria suggestive of glomerulonephritis. A diagnosis of fibrillary glomerulonephritis was made on renal biopsy. Fibrillary glomerulonephritis is a rarely diagnosed disease with clinical manifestations such as proteinuria, microscopic haematuria, nephrotic syndrome and impairment of renal function. A diagnosis of fibrillary glomerulonephritis can only be made by electronmicroscopy of the renal tissue. In this case report the spectrum of this disease is reviewed. |
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