弥漫性泛细支气管炎的临床影像1例报道及文献复习

目的探讨弥漫性泛细支气管炎（DPB）的临床与影像学表现，以提高对本病的认识。方法对1例经病理证实并有完整的临床、实验室及肺功能检查、胸片及高分辨率CT（HRCT）检查的弥漫性泛细支气管炎进行回顾性分析。结果1例临床表现为咳嗽、咯痰及活动后气短。胸片示两肺弥漫性分布的小结节影及肺过度充气膨胀并两下肺支气管扩张，HRCT像示：①肺小叶中心性小结节影；②小支气管和细支气管扩张；③支气管壁增厚。同时伴有副鼻窦炎或既往有副鼻窦炎病史。结论密切结合临床表现、实验室检查、肺功能检查及胸部、副鼻窦影像学表现，有助于本病的早期诊断，DPB的确诊仍依赖于病理组织学检查。

Clinic and Imaging Findings of Diffuse Panbronchiolitis (A Report of 1 Cases and Literature Review)

Objective To make a further understanding of diffuse panbronchiolitis （DPB） by analyzing its clinical and imaging manifestations. Methods The clinical and laboratory data,including lung function test,as well as the findings on chest films and HRCT scans in 1 cases with pathologically-proved DPB were retrospectively analyzed. Results One cases presented clinically coughing, sputum, shortness of breath on exertion and paranasal sinusitis or a history of previous paranasal sinusitis. Diffusely distributed fine nodules,hyperinflation of the lungs and bronchiectasis of lower fields were seen on chest films. Findings on HRCT scans were as follows： （ 1 ） central nodules in lobules; （2） bronchiectasis and bronchiolectasis ; （3） thickening of bronchial wall. Conclusion Correct diagnosis of DPB should be based on pathologic study, although clinical and laboratory data, as well as imaging findings are very helpful.