87例妊娠梅毒患者临床特征和妊娠结局的回顾性分析

对我院2015年1月1日至2018年12月31日诊治的87例妊娠梅毒患者的临床资料进行回顾性分析，结果示潜伏梅毒80例，一期梅毒和二期梅毒患者分别为4例和3例。潜伏梅毒患者中RPR滴度≤1:4者59例，≥1:8者21例。一期梅毒和二期梅毒患者中RPR滴度≤1:4者1例，≥1:8者6例；87例患者中，72例（82.76%）在孕期进行了抗梅毒治疗。妊娠梅毒患者的不良妊娠结局发生率为23.53%，其中先天梅毒的发生率为3.80%。RPR滴度、梅毒诊断孕周及治疗情况与不良妊娠结局的发生相关(均P＜0.05)。

Retrospective analysis of pregnancy outcomes of 87 patients with pregnancy syphilis

The data of 87 pregnant syphilis patients in our hospital diagnosed from January 1st, 2015 to December 31, 2018 was analyzed retrospectively. Of 87 patients, 80 were latent syphilis, 4 were pristmary syphilis, and 3 were secondary syphilis. Of 80 latent syphilis patients, the RPR titer was ≤1:4 in 59 patients, ≥1:8 in 21. Of the 7 primary syphilis and secondary syphilis patients, the RPR titer was ≤1:4 in one patient and ≥1:8 in 6 patients. Of 87 patients, 72 (82.76%) patients were treated during pregnancy. The occurence adverse pregnancy outcomes was 23.53%, of which congenital syphilis accunted for 3.80%. The serum RPR titer, gestational weeks at the time of syphilis diagnosis, and treatment were associated with the adverse pregnancy outcome (Ps<0.05).