无肌病性皮肌炎一例

患者,女，21岁。面部、躯干、四肢皮肤红斑、丘疹伴脱发6年，皮损基本损害为红斑，双眼睑见明显水肿性紫红斑，其他部位皮损为弥漫性对称性暗紫红色斑，双手可见Gottron丘疹。肌力正常。皮损组织病理检查：表皮轻度角化过度，基底膜增厚，真皮浅层水肿，血管周围单一核细胞浸润。诊断：无肌病性皮肌炎。给予泼尼松联合甲氨蝶呤治疗2个月后皮损明显好转。

Amyopathic dermatomyositis:a case report

A 21-year-old female patient presented with erythema and papules on her face, trunk and limbs with alopecia for six years. The lesions mainly manifested as erythema, dropsical heliotrope rash on the double eyelids. The lesions on the trunk and limbs were diffuse symmetry heliotrope rash. Gottron’s papules on the hands. The muscle strength was normal. Histopathologic findings revealed mild hyperkeratosis, basal thickening, upper dermis edema and infiltration of mononuclear cells in the superficial blood vessels. The diagnosis of amyopathic dermatomyositis was made. The patient was treated with prednisone and methotrexate, and the skin lesions were significantly improved after two months.